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Keep your cholesterol
in check with Simvastatin
Cholesterol is a myth which
induces a sense of apprehension because of its literally split
personality-like functioning in the body...
Date : February 10, 2006
Cholesterol is a myth which
induces a sense of apprehension because of its literally split
personality-like functioning in the body. Cholesterol
is a lipid - a waxy-fatty substance found in the membrane
of the cells in our body. The body needs cholesterol for digesting
dietary fats, making hormones and strengthening cell walls.
But on reaching high levels, it can lead to atherosclerosis
and increase the risk of cardiovascular disease.
An average person makes 75%
of blood cholesterol in the liver and 25% is absorbed from
food intake. Though fat plays the biggest influence in high
cholesterol level, it is to be clarified that fats are a source
of energy and the harmful fats are the saturated fats derived
primarily from meat, dairy products and some vegetable oils
made from coconut, palm and cocoa. Cholesterol throughout
the body is transported in the bloodstream by lipoproteins
such as low density lipoproteins (LDL) and high density lipoproteins
(HDL).
Cholesterol in blood is categorized
as 'good' and 'bad' depending upon the function of liver.
LDL referred to as the "bad" cholesterol carry cholesterol
from the liver to the rest of the body. When there is excess
LDL cholesterol in the blood, it combines
with other substances and sticks to the walls of arteries
forming plaque which narrow an artery enough to slow or block
blood flow leading to the condition atherosclerosis. The desirable
LDL is 100mg/dl and high is 160-189mg/dl. On the other hand,
HDL referred to as the 'good' cholesterol extracts cholesterol
particles from the artery walls and transports them back to
the liver to be disposed through the bile, thus protecting
the arteries from the atherosclerosis process. The desirable
HDL is above 60mg/dl and undesirable is below 40mg/dl.
Many factors such as genetic,
obesity, inactive lifestyle
and unhealthy diet contribute to high cholesterol. Therapeutic
changes in lifestyle like weight loss, regular exercise, not
smoking and following a low saturated fat and cholesterol
can help in maintaining a low cholesterol level. Drug therapy
is prescribed only when lifestyle changes cannot reduce the
LDL cholesterol to desired levels.
The most prominent cholesterol
drugs belong to the statin family, including Simvastatin
and Atorvastatin to
name a few. Medical studies reveal that, statin drugs work
by interfering with the cholesterol-producing mechanisms of
the liver by increasing the capacity of the liver to remove
cholesterol from circulating blood. Simvastatin, the most
commonly used cholesterol lowering drug is available under
the brand name Zocor. It is a prescription drug which inhibits
the production of cholesterol by the liver; reduce coronary
heart disease events and deaths due to heart attack. Simvastatin
should be taken only under medical guidance to prevent drug
interaction and related side effects.
Cholesterol can be both good
and bad. So to control your cholesterol, understand the facts
about cholesterol - get a cholesterol screening, eat foods
low in saturated fat and cholesterol, maintain a healthy weight,
exercise regularly and follow all your healthcare professional's
recommendations.
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