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Zolpidem

Generic Name: Zolpidem
Brand Name: Ambien

Zolpidem is a prescription drug used for the short-term treatment of insomnia (sleeplessness). Zolpidem is closely related to a family of drugs called benzodiazepines. Zolpidem helps to treat trouble falling asleep, waking up too early in the morning, or waking up too often during the night and is approved for the short-term treatment.

How Is It Used?
Take by mouth, better to take it on an empty stomach (without food). Follow the directions on the prescription label. Swallow the tablets with a drink of water. Take only the prescribed dose, exactly as instructed by your doctor.

Are There Possible Side Effects?
The most common side effects of Zolpidem are drowsiness, diarrhea, dizziness, headache and a "drugged" feeling, which probably reflect the action of the drug.

Other side effects include confusion, depression mood, lightheadedness, euphoria, ataxia (balance problems), and visual changes.

Some side effects can be serious: rash, hives, itching, pounding heartbeat, chest pain, fever. If you experience any of these symptoms, call your doctor immediately.

What particular precautions should I follow?

  • Let your doctor know if you are allergic to any medications and what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking right now or plan to take. Be sure to mention any of the following: antidepressants ('mood elevators') such as imipramine (Tofranil); itraconazole (Sporanox); medications for anxiety, colds or allergies, mental illness, pain, or seizures; rifampin (Rifadin, Rimactane); sedatives; sertraline (Zoloft);sleeping pills; and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • Tell your doctor if you drink or have ever drunk large amounts of alcohol, use or have ever used street drugs, or have overused prescription medications. Also tell your doctor if you have or have ever had depression, sleep apnea (condition in which the patient briefly stops breathing many times during the night), other breathing problems, or liver or kidney disease. Do not drink alcohol during your treatment with zolpidem. Alchohol can make the side effects of zolpidem worse.
  • Tell your doctor if you are pregnant or plan to become pregnant. If you become pregnant while taking zolpidem, call your doctor. Do not breastfeed while you are taking zolpidem.
  • Tell the doctor or dentist that you are taking zolpidem, if you are having surgery, including dental surgery.
  • You should know that zolpidem may make you drowsy during the day, and may increase the risk that you will fall. Take extra care not to fall and do not drive a car or operate machinery until you know how this medication affects you.
  • You should know that your mental health may change in unexpected ways while you are taking this medication. It is hard to tell if these changes are caused by zolpidem or if they are caused by physical or mental illnesses that you already have or suddenly develop. Tell your doctor right away if you experience any of the following symptoms: aggressiveness, strange or unusually outgoing behavior, hallucinations (seeing things or hearing voices that do not exist), feeling as if you are outside of your body, memory problems, difficulty concentrating, slowed speech or movements; new or worsening depression, thinking about killing yourself, confusion, and any other changes in your usual thoughts, mood, or behavior. Be sure that your family knows which symptoms may be serious so that they can call the doctor if you are unable to seek treatment on your own.

What about Interactions with Other Drugs?
Tell your doctor about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your doctor if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works.

  • Bupropion
  • caffeine
  • certain antidepressants, like citalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, or venlafaxine
  • flumazenil
  • medications for fungal infections, like ketoconazole, fluconazole, or itraconazole
  • some medicines used to treat HIV infection or AIDS, like ritonavir
  • St. John's wort

Certain medications may cause additive drowsiness or decrease alertness with zolpidem:

  • Alcohol
  • allergy, cough, or cold medications (antihistamines)
  • kava kava
  • melatonin
  • medicines for anxiety
  • medicines for pain
  • medicines for treating mental problems
  • melatonin
  • other sedatives given for sleep
  • some medicines for Parkinson' s disease or other movement disorders
  • valerian

In case of emergency/overdose
In case of overdose and if the patient has collapsed or is not breathing, immediate call local emergency services.

Symptoms of overdose are drowsiness, coma (loss of consciousness for a period of time), slowed breathing or heartbeat.

What If I Miss A Dose?
This does not apply. Zolpidem should only be taken immediately before going to sleep. Do not take twice or extra doses.

How Should It Be Stored?
Zolpidem should be stored at room temperature in a tight container, tightly closed, and out of reach of children. Expired medicines should be thrown away.

Anything Else I Should Know?
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

NOTE: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It should not be construed to indicate that the use of the product is safe, appropriate, or effective for you. Consult your healthcare professional before taking the product.



 

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